by Blackwell Publishing .
Written in English
|The Physical Object|
|Number of Pages||290|
The groundbreaking new book that covers platelets, their role, and their study through proteomics research Platelets are defined as small anucleate cells that circulate in the blood and play a fundamental role in haemostasis and thrombosis.5/5(1). COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle . The intended audience for The Non-Thrombotic Role of Platelets in Health and Disease includes platelet biologists, microbiologists, immunologists, haematologists, oncologists, respiratory physicians, cardiologists, neurobiologists, tissue engineers, as well as students and fellows in these areas. Read more > Order hardcopyCited by: 1. Platelets are also important for vascular repair and remodeling. The vasoactive substances that platelets release may play protective or damaging roles depending on the circumstances surrounding platelet activation. Platelets are active effector cells in wound healing and can also play roles in angiogenesis and vascular repair and remodeling. Some of these actions, when Author: Brian P. O’Sullivan, Steven W. Kerrigan.
Usually dispatched within 3 to 5 business days. This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in Edition: 3. Members of the Platelet Society are actively engaged in researching all aspects of platelet biology, from how they are made to how they work normally and how they go wrong in disease. Our goal is to use the results of our research to develop better strategies and medicines to prevent and treat thrombosis. This article summarizes recent ultrastructure findings from our laboratory and documents some of the information accumulated primarily since from many laboratories. Special attention is given to documentation by scanning electron microscopy which affords insight into platelet activation (adhesion, aggregation, release/secretion) and especially platelet Cited by:
Platelets become Activated by Stimulation with Low and High Doses of Aß. To determine the impact of soluble Aß on platelet activation we first performed electron microscopy and confirmed morphological changes of platelets after incubation with Aß for 24 hrs. In contrast to the platelet suspension without stimulus, Aß-treated platelets showed typical characteristics of activated platelets Cited by: Hereditary disorders of platelet function consist of von Willebrand disease, the most common hereditary hemorrhagic disease, and hereditary intrinsic platelet disorders, which are much less common. Acquired disorders of platelet dysfunction are commonly due to diseases (eg, renal failure) as well as to aspirin and other drugs. Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Discrepant results have been published concerning platelet membrane fluidity: while decreased fluidity of cell membranes from platelets is associated with normal ageing, increased internal membrane fluidity is one of the first alterations to be reported in platelets [25, 26]. Increased platelet membrane fluidity becomes apparent by a decrease in the fluorescence anisotropy Cited by: 2.